positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
Involvement in disease:Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
(predicted: Human,Mouse,Rat,Rabbit)
IHC-P,ELISA,IHC-F,IF
Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.